Histopathological and immunohistochemical study of laterocervical lymph node metastases of unknown primary origin.
نویسندگان
چکیده
In this study, we examined histopathologically and immunohistochemically 24 cases of laterocervical lymph node metastases with unknown primary origin. For immunohistochemical study, we used a large panel of antibodies represented by CK7, CK19, CK20, CKAE1/AE3, CK34betaE12, TTF1, HBME-1, CEA, MUC5AC and EBV. In the cases studied tumors accompanied by seemingly primitive adenopathies were located in the thyroid, lung, esophagus, stomach, rhinopharynx, hypopharynx, oropharynx and larynx.
منابع مشابه
Squamous Cell Differentiation in Metastatic Papillary Thyroid Carcinoma: Metaplastic
Squamous cell differentiation (SCD) may occur in papillary thyroid carcinoma (PTC) only at metastatic sites. We have studied cytokeratin CK5/6 and P63 along with TTF1 (thyroid transcription factor 1) and B-Raf (V-Raf murine sarcoma viral oncogene homolog B1) immunohistochemical expression in neck lymph node metastases of thyroid PTC showing SCD. The patient (21-years) presented wit...
متن کاملDiagnostic Features and Subtyping of Thymoma Lymph Node Metastases
AIM The purpose of the present study was to characterize the morphological features of thymoma metastases in lymph nodes and to evaluate the possibility of their subtyping according to the 2004 WHO classification of thymus tumors. MATERIALS AND METHODS We reviewed 210 thymoma cases in our series of thymic epithelial tumors (TET), including their recurrences and lymphogenous metastases. Three ...
متن کاملبیوپسی غده لنفاوی نگهبان کشاله ران فقط با ایزوسولفان بلو در ملانوم بدخیم اندام تحتانی
Background: Sentinel lymph node (SLN) biopsy has become the standard of care in malignant melanoma, it is commonly identified by intradermal injection of both radiocolloid tracer and Patent Blue Dye (PBD) around the tumor. This study aims to evaluate the efficacy of PBD in identifying inguinal SLN and also the accuracy of SLN mapping performed by peritumoral injection of PBD without combined ra...
متن کاملDiagnostic performance of 18F-FDG PET-CT in patients presenting with secondary neck nodes from an unknown primary
Introduction: Clinical examination and even anatomical imaging may fail to identify primary site of malignancy in patients presenting with cervical nodal metastasis. 18F-Fluorodeoxyglucose Positron Emission Computed Tomography (18F-FDG PET-CT) is known to overcome the limitations of anatomic imaging. Methods: Sixty-three (63) patient...
متن کاملMetastatic carcinoma with unknown primary – does immunohistochemistry help to detect origin?
Carcinoma of unknown primary is a common clinical problem. They are often the first symptom of systemic malignancy. Hence, immunohistochemistry (IHC) is of importance in evaluating the primary origin. The aim was to detect the primary site of metastatic carcinoma and evaluate the role of IHC in diagnosing the same. Cases of metastatic carcinoma of unknown primary to lymph node, bone and parieti...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
دوره 53 2 شماره
صفحات -
تاریخ انتشار 2012